{"id":1452,"date":"2018-06-05T10:47:44","date_gmt":"2018-06-05T08:47:44","guid":{"rendered":"https:\/\/blog.ki.se\/rektor\/?p=1452"},"modified":"2018-06-05T10:47:44","modified_gmt":"2018-06-05T08:47:44","slug":"artikeln-i-respiration-maste-dras-tillbaka","status":"publish","type":"post","link":"https:\/\/blog.ki.se\/rektor\/2018\/06\/05\/artikeln-i-respiration-maste-dras-tillbaka\/","title":{"rendered":"Artikeln i Respiration m\u00e5ste dras tillbaka"},"content":{"rendered":"

Den 28 november 2015 publicerade den vetenskapliga tidskriften Respiration artikeln\u00a0\u201cAutologous peripheral blood mononuclear cells as treatment in refractory acute respiratory distress syndrome\u201d\u00a0<\/em>(Respiration 2015; 90:481-492). Huvudf\u00f6rfattare var Paolo Macchiarini, som vid denna tid hade en tidsbegr\u00e4nsad anst\u00e4llning vid Karolinska Institutet. Han avskedades i mars \u00e5ret efter, efter att en rad missf\u00f6rh\u00e5llanden och grova felaktigheter uppdagats i samband med hans verksamhet p\u00e5 Karolinska Institutet och Karolinska Universitetssjukhuset. Se en sammanfattning av Macchiarini-\u00e4rendet i den tidslinje som finns publicerad p\u00e5 KI:s webbplats<\/a>.<\/p>\n

Efter utredning beslutade jag i januari i \u00e5r att Macchiarini och tre av hans medf\u00f6rfattare skulle f\u00e4llas f\u00f6r oredlighet i forskning utifr\u00e5n inneh\u00e5llet i artikeln. I motiveringen framh\u00e5lls bland annat att \u201dPaolo Macchiarini, som huvudf\u00f6rfattare och initiativtagare till forskningsinsatsen, har ett s\u00e4rskilt stort ansvar f\u00f6r den oredlighet som konstaterats. Det var han som hade det huvudsakliga forskningsintresset i den h\u00e4ndelseutveckling som f\u00f6regick artikeln och som fick m\u00f6jlighet att genomf\u00f6ra experiment av preklinisk natur p\u00e5 en m\u00e4nniska\u201d.<\/p>\n

I samband med beslutet meddelade jag \u00e4ven i ett brev till ansvarig redakt\u00f6r f\u00f6r Respiration om bakgrunden till beslutet och beg\u00e4rde att artikeln skulle dras tillbaka.\u00a0Detta \u00e4r en artikel som kan leda till felaktig behandling och lidande f\u00f6r framtida patienter. Det \u00e4r tidskriftens ansvar att den dras tillbaka. Artikeln anger att etiktillst\u00e5nd finns, n\u00e4r detta gavs betydligt senare och\u00a0\u00e4r begr\u00e4nsat till den hantering av personliga uppgifter som skedde flera \u00e5r efter behandlingen.\u00a0Den forskning som genomf\u00f6rts p\u00e5 den sv\u00e5rt sjuka patienten saknar varje form av etiskt tillst\u00e5nd.<\/p>\n

Eftersom tidskriften trots ett antal p\u00e5pekanden fortfarande inte dragit tillbaka den aktuella artikeln, v\u00e4ljer jag h\u00e4r att publicera delar av den dialog jag haft med tidskriftens ansvariga.<\/p>\n

Fr\u00e5n Respiration (6 februari 2018):<\/strong><\/h4>\n

\u201dDear Professor Ottersen,<\/em><\/p>\n

We have received a request\u00a0from the Karolinska Institutet to retract the above article. At the same time, we have been contacted by one\u00a0of the authors\u00a0asking us to delay our decision regarding this matter.<\/em><\/p>\n

The Editors and the publishing house are both of the opinion that it is the journal\u2019s duty\u00a0 to the scientific community to provide a platform for discussions and a forum for debating. Furthermore, the background of the conflict between the two parties should be transparent to the readers to enable them to\u00a0form their own\u00a0opinion.<\/em><\/p>\n

Therefore, we would like to ask all parties concerned to write a \u2018Letter to the Editor\u2019 pertaining to this conflict for simultaneous publication. The maximum length should be 4 manuscript pages with the possibility of supplementary online material. The article in question along with the Letters will be \u2018Free Access\u2019 with reciprocal links between the article and the Letters. Deadline for receipt of the Letters is the end of February 2018. Please submit to the Editorial Office as an email attachment.<\/em><\/p>\n

We sincerely hope that both parties will take advantage of this offer to present their viewpoint.<\/em><\/p>\n

With best regards,<\/em><\/p>\n

Linda Haas<\/em><\/p>\n

Editorial Office \u2018Respiration\u2019<\/em><\/p>\n

Mitt svar (23 februari 2018):<\/strong><\/h4>\n

Dear Editor<\/em><\/p>\n

Thank you for your letter. We are not interested in engaging in a discussion about this matter. Our request for retraction is based on a formal decision by the Rector\/Vice-Chancellor. We uphold our request and look forward to learn about your final decision.<\/em><\/p>\n

In case you choose not to comply with our request we would like to know your arguments for this.<\/em><\/p>\n

Best regards<\/em><\/p>\n

Ole Petter Ottersen<\/em><\/p>\n

Fr\u00e5n Respiration (10 mars 2018):<\/strong><\/h4>\n

Dear Professor Ottersen,\u00a0<\/em><\/p>\n

Thank you for your reply.\u00a0<\/em><\/p>\n

We would to emphasise that we have taken your request for the retraction of this article very seriously, however, we found it only fair to all parties concerned to offer the option of publishing a letter on this matter in question.\u00a0<\/em><\/p>\n

We believe, that based on the evidence available to the journal, we are not in a position to make a judgement on whether or not to retract this article. We have, therefore, decided to leave it up to our readers to build their own opinion on the matter and decide for themselves with regard to the validity of the conclusions. We do not want to patronize the readers of the journal \u2018Respiration\u2019.<\/em><\/p>\n

Finally, we would like to ask you to reconsider your decision not to engage in any discussion. If you decision remains unchanged, we would like to ask for your consent to publish your retraction request in the journal \u2018Respiration\u2019.<\/em><\/p>\n

Yours sincerely,<\/em><\/p>\n

Professor Felix J.F. Herth<\/em><\/p>\n

Editor-in-Chief<\/em><\/p>\n

Thomas H. Nold<\/em><\/p>\n

On behalf of S. Karger Publishers<\/em><\/p>\n

Mitt svar (4 april 2018):<\/strong><\/h4>\n

Dear Editor<\/em><\/p>\n

Thank you for your mail.<\/em><\/p>\n

We uphold our claim that the paper be retracted. We would like to be informed about the journal\u2019s policy in such matters. This issue has a bearing on important ethical principles and we are surprised at your response to our request.<\/em><\/p>\n

In our investigation we have solicited and received comments from all authors, and they have all been informed about our decision. Our decision is final and we see no reason why we should\u00a0 engage in a further discussion in your journal.<\/em><\/p>\n

Obviously you are free to publish our report if you so wish.<\/em><\/p>\n

Sincerely<\/em><\/p>\n

Ole Petter Ottersen<\/em><\/p>\n

Faller p\u00e5 sin egen orimlighet<\/strong><\/h4>\n

Jag \u00e4r b\u00e5de \u00f6verraskad och besviken \u00f6ver svaren fr\u00e5n Respiration. Det h\u00e4r r\u00f6r sig om en artikel som \u00e4r baserad p\u00e5 en konstaterad oetisk forskning som skett utan etisk pr\u00f6vning eller tillst\u00e5nd och som orsakat on\u00f6digt lidande f\u00f6r en sv\u00e5rt skadad patient. En s\u00e5dan artikel m\u00e5ste dras tillbaka. Att bjuda in till en \u201dvetenskapligt diskussion\u201d om detta faller p\u00e5 sin egen orimlighet.<\/p>\n

Den som f\u00f6ljt bloggen vet att vi tidigare denna v\u00e5r haft en intensiv diskussion om \u201dLars Andersson<\/a>\u201d och om vilken praxis och rutin en vetenskaplig tidskrift b\u00f6r ha<\/a>. Handlar det om n\u00e5gon form av fusk, oegentligheter, falsarier eller oredlighet, b\u00f6r detta ocks\u00e5 f\u00e5 konsekvenser n\u00e4r det g\u00e4ller publiceringar.<\/p>\n

Ansvaret f\u00f6r forskningsverksamhet och etik vilar tungt p\u00e5 l\u00e4ros\u00e4tena, det \u00e4r vi \u00f6verens om. Om en pr\u00f6vning av en forskningsverksamhet vid ett universitet leder fram till ett beslut om oredlighet, m\u00e5ste detta ocks\u00e5 synas och m\u00e4rkas i de publiceringar som skett inom denna verksamhets dom\u00e4ner.<\/p>\n

I fallet \u201dLars Andersson\u201d har tv\u00e5 av tre tidskrifter tagit sitt ansvar och utifr\u00e5n ett etiskt st\u00e4llningstagande beslutat att dra tillbaka artiklarna.<\/p>\n

F\u00f6r mig \u00e4r det sj\u00e4lvklart att Respiration ska g\u00f6ra samma sak.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Den 28 november 2015 publicerade den vetenskapliga tidskriften Respiration artikeln\u00a0\u201cAutologous peripheral blood mononuclear cells as treatment in refractory acute respiratory distress syndrome\u201d\u00a0(Respiration 2015; 90:481-492). Huvudf\u00f6rfattare var Paolo Macchiarini, som vid […]<\/p>\n","protected":false},"author":100,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[128,250,26],"tags":[253,242,237,225],"class_list":["post-1452","post","type-post","status-publish","format-standard","hentry","category-ethics","category-publishing","category-research","tag-articles","tag-ethics","tag-etik","tag-forskning"],"acf":[],"yoast_head":"\nArtikeln i Respiration m\u00e5ste dras tillbaka - Ole Petter Ottersen, president Karolinska Institutet 2017-2023<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.ki.se\/rektor\/2018\/06\/05\/artikeln-i-respiration-maste-dras-tillbaka\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Artikeln i Respiration m\u00e5ste dras tillbaka - Ole Petter Ottersen, president Karolinska Institutet 2017-2023\" \/>\n<meta property=\"og:description\" content=\"Den 28 november 2015 publicerade den vetenskapliga tidskriften Respiration artikeln\u00a0\u201cAutologous peripheral blood mononuclear cells as treatment in refractory acute respiratory distress syndrome\u201d\u00a0(Respiration 2015; 90:481-492). 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