{"id":1464,"date":"2018-06-05T22:40:19","date_gmt":"2018-06-05T20:40:19","guid":{"rendered":"https:\/\/blog.ki.se\/rektor\/?p=1464"},"modified":"2018-06-06T17:45:08","modified_gmt":"2018-06-06T15:45:08","slug":"inget-samband-mellan-okad-cancerincidens-och-hpv-vaccinationer","status":"publish","type":"post","link":"https:\/\/blog.ki.se\/rektor\/2018\/06\/05\/inget-samband-mellan-okad-cancerincidens-och-hpv-vaccinationer\/","title":{"rendered":"Inget samband mellan \u00f6kad cancerincidens och HPV-vaccinationer"},"content":{"rendered":"

English version below<\/strong><\/p>\n

Joakim Dillner, professor och verksam vid institutionen f\u00f6r laboratoriemedicin h\u00e4r p\u00e5 Karolinska Institutet, har nu publicerat en studie om \u00f6kningen av cervixcancer i Sverige. Som v\u00e4ntat kan alla samband mellan den \u00f6kade incidensen och inf\u00f6randet av HPV-vaccination avskrivas.<\/p>\n

P\u00e5 senare \u00e5r har antalet fall av cervixcancer (livmoderhalscancer) \u00f6kat i Sverige med cirka 20 procent. M\u00e4tt i absoluta tal handlar det om en \u00f6kning fr\u00e5n omkring 450 \u00e5rliga fall till 550. Dillner har, tillsammans med tre forskarkollegor, analyserat data fr\u00e5n det nationella kvalitetsregistret f\u00f6r cervixcancerprevention f\u00f6r att om m\u00f6jligt kunna se vad som kan f\u00f6rklara incidens\u00f6kningen.<\/p>\n

J\u00e4mf\u00f6relse\u00a0<\/b><\/h4>\n

Eftersom det under v\u00e5ren spritts uppgifter om att inf\u00f6randet av HPV-vaccinationer skulle kunna vara en f\u00f6rklaring till \u00f6kningen, n\u00e5got som fr\u00e4mst den falske forskaren \u201dLars Andersson\u201d kastade fram en teori om, har forskarna gjort en j\u00e4mf\u00f6relse mellan data i kvalitetsregistret och data i HPV-vaccinationsregistret. Denna j\u00e4mf\u00f6relse visar utan tvekan att andelen kvinnor som f\u00e5tt cervixcancer \u00e4r betydligt st\u00f6rre i gruppen som inte har vaccinerat sig, j\u00e4mf\u00f6rt med den grupp som har vaccinerat sig.<\/p>\n

H\u00e4r ska dock s\u00e4gas att en delf\u00f6rklaring till detta sannolikt \u00e4r att de som v\u00e4ljer att vaccinera sig redan fr\u00e5n b\u00f6rjan har en relativt sett l\u00e4gre risk f\u00f6r att f\u00e5 cancer. Det \u00e4r kvinnor som redan har en stor medvetenhet om vilka f\u00f6reteelser (levnadsvanor, livsvillkor, andra preventiva insatser och f\u00f6ruts\u00e4ttningar) som kan leda till \u00f6kad cancerrisk.<\/p>\n

Endast enstaka fall<\/strong><\/h4>\n

Men vad som \u00e4r helt entydigt \u00e4r att HPV-vaccination inte kan ha orsakat n\u00e5gon \u00f6kning av antalet cancerfall: I den \u00e5ldersgrupp d\u00e4r vi fr\u00e4mst ser \u00f6kningen (kvinnor f\u00f6dda 1965-1984) har f\u00e5 tagit vaccinet och bland dem som tog vaccinet var det endast n\u00e5gra enstaka fall av cervixcancer.<\/p>\n

Vad \u00e4r d\u00e5 orsaken till den \u00f6kande incidensen? En m\u00f6jlig f\u00f6rklaring skulle kunna finnas i den anm\u00e4rkningsv\u00e4rda skillnad i incidens mellan landstingen, som Dillner et al redovisar: \u201dDetta tyder p\u00e5 att \u00f6kningen kan vara relaterad till de regionalt organiserade screeningsprogrammen\u201d, skriver forskarna i artikeln, som publicerades i L\u00e4kartidningen i tisdags.<\/p>\n

Forskargruppen kommer nu att arbeta vidare med data f\u00f6r att kunna ge en klarare bild av t\u00e4nkbara f\u00f6rklaringar till \u00f6kningen av incidensen f\u00f6r cervixcancer.<\/p>\n

 <\/p>\n

No correlation between increased cancer incidence and HPV vaccinations<\/strong><\/h2>\n

Joakim Dillner, professor at the Department of Laboratory Medicine here at Karolinska Institutet, has now published a study on the increase of cervical cancer in Sweden. As expected, there is no evidence to suggest that the increased cancer incidence is related to the introduction of HPV vaccination.<\/p>\n

In recent years, the number of cases of cervical cancer has increased in Sweden by about 20 percent. Measured in absolute terms, there has been an increase from about 450 cases annually to about 550. Dillner and his colleagues have analyzed data from the Swedish National Quality Registry for Cervical Cancer Prevention (Nationella kvalitetsregistret f\u00f6r cervixcancer prevention) to search for an explanation of the increased incidence of cervical cancer.<\/p>\n

No support<\/strong><\/h4>\n

The claim that the increased cancer incidence could be related to the introduction of HPV vaccination \u2013 a claim put forward by the false researcher \u201cLars Andersson\u201d \u2013 finds no support in Dillner\u2019s analysis. Comparisons between data in the quality register and data in the Swedish HPV vaccination register clearly show that the proportion of women with cervical cancer is significantly higher in the non-vaccinated group, compared with the vaccine group.<\/p>\n

Those that choose vaccination might have a lower a priori cancer risk than those that don\u2019t. Thus the former group might have a greater awareness of putative risk factors for cancer compared with the latter group. This might have contributed to the differences observed.<\/p>\n

Only occasional cases<\/strong><\/h4>\n

But what is absolutely clear is that HPV vaccination cannot be responsible for the increase in cancer incidence. In the age group with the most significant increase (women born 1965-1984), few have taken the vaccine and among those who took the vaccine there were only occasional cases of cervical cancer.<\/p>\n

Dillner and his colleagues will now perform further analyses in an attempt to better explain the mechanisms underlying the increased incidence of cervical cancer in Sweden.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

English version below Joakim Dillner, professor och verksam vid institutionen f\u00f6r laboratoriemedicin h\u00e4r p\u00e5 Karolinska Institutet, har nu publicerat en studie om \u00f6kningen av cervixcancer i Sverige. Som v\u00e4ntat kan […]<\/p>\n","protected":false},"author":100,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[160,33,250,26],"tags":[253,225,263,30],"class_list":["post-1464","post","type-post","status-publish","format-standard","hentry","category-halso-och-sjukvard","category-health-care","category-publishing","category-research","tag-articles","tag-forskning","tag-hpv-vaccination","tag-research"],"acf":[],"yoast_head":"\nInget samband mellan \u00f6kad cancerincidens och HPV-vaccinationer - Ole Petter Ottersen, president Karolinska Institutet 2017-2023<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.ki.se\/rektor\/2018\/06\/05\/inget-samband-mellan-okad-cancerincidens-och-hpv-vaccinationer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Inget samband mellan \u00f6kad cancerincidens och HPV-vaccinationer - Ole Petter Ottersen, president Karolinska Institutet 2017-2023\" \/>\n<meta property=\"og:description\" content=\"English version below Joakim Dillner, professor och verksam vid institutionen f\u00f6r laboratoriemedicin h\u00e4r p\u00e5 Karolinska Institutet, har nu publicerat en studie om \u00f6kningen av cervixcancer i Sverige. 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