{"id":3180,"date":"2019-10-21T17:26:05","date_gmt":"2019-10-21T15:26:05","guid":{"rendered":"https:\/\/blog.ki.se\/rektor\/?p=3180"},"modified":"2019-10-21T17:26:05","modified_gmt":"2019-10-21T15:26:05","slug":"redefining-research-quality-reproducibility-and-beyond","status":"publish","type":"post","link":"https:\/\/blog.ki.se\/rektor\/2019\/10\/21\/redefining-research-quality-reproducibility-and-beyond\/","title":{"rendered":"Redefining research quality: Reproducibility and beyond"},"content":{"rendered":"<p>We are in the midst of what some have called a research reproducibility crisis. While scientific discovery and complexity are developing at an unprecedented speed, less than 50% of scientific research studies can be reliably replicated. Left unchecked, this troubling fact may threaten our ability to generate sound, evidence-based knowledge that meets society\u2019s needs. It is time to look beyond the traditional measures of quality and re-examine the very concept of quality itself.<\/p>\n<p>Tuesday October 22nd, KI is proud to host university presidents and directors from around the country at the annual Association of Swedish Higher Education Institutions (SUHF) conference: <strong>Redefining research quality: The reproducibility challenge<\/strong><strong>.<\/strong><\/p>\n<p>Throughout the day we will shine a light on these urgent challenges\u00a0together with experts John\u00a0Ioannidis (Stanford University Department of Medicine), Anna Dreber Almenberg (Stockholm School of Economics),\u00a0Glenn Begley (BioCurate Pty Ltd) and Sweden\u2019s Minister for Higher Education &amp; Research Matilda Ernkrans, among others.<\/p>\n<p>We\u2019ll also explore strategies for developing a more nuanced understanding of quality \u2013 one that takes into account the need for soundness and replicability, for better study designs and more appropriate statistical methods,\u00a0for proactive ethical and critical reflection, and\u00a0for more open and democratic access to scientific results.<\/p>\n<p>If KI is to remain a leading medical university and societal actor, it is paramount that we continue to make space for critical reflection and open discussions about the very nature of research quality \u2013 for it is quality that provides the foundation for groundbreaking discoveries, world-class education, and the translation of evidence-based knowledge into societal benefits.<\/p>\n<p>By deeply examining the factors that can threaten or strengthen the soundness of scientific research, we can begin to take greater responsibility for fostering the very best academic research practice.<\/p>\n<p>Conference speakers and points:<\/p>\n<p><strong>10:00 Welcome: <\/strong>Astrid S\u00f6derbergh Widding, SUHF Board Chair and President, Stockholm University<\/p>\n<p><strong>10:10 Redefining the concept of medical research quality, <\/strong>Ole Petter Ottersen, President, Karolinska Institutet<\/p>\n<p><strong>10:20 The \u201creproducibility crisis\u201d in academic research, <\/strong>John P.A. Ioannidis, Professor of Medicine, Co-Director, Meta-Research Innovation Center, Stanford University<\/p>\n<p><strong>\u00a0<\/strong><strong>11:30 Which results can we trust? Using replications and prediction markets to assess the reliability of scientific results, <\/strong>Anna Dreber Almenberg, Johan Bj\u00f6rkman Professor of Economics, Stockholm School of Economics<\/p>\n<p><strong>12:00 Challenges for basic and preclinical research, <\/strong>C. Glenn Begley, MD, CEO of BioCurate (via video link)<\/p>\n<p><strong>12:15 Reflections and discussion<\/strong>, C. Glenn Begley, Gustav Nilsonne &amp; Carl Johan Sundberg<\/p>\n<p><strong>\u00a0<\/strong><strong>13:30 Research quality from a national perspective, <\/strong>Matilda Ernkrans, Minister for Higher Education &amp; Research<\/p>\n<p><strong>13:50 Panel: The multiple faces of research quality:<\/strong> <strong>Preconditions, hallmarks and outcomes<br \/>\n<\/strong>Moderator: Carl Johan Sundberg, Professor, KI<br \/>\nAgneta Bladh, Board Chair, Swedish Research Council<br \/>\nSten Linnarsson, Professor, KI\/MBB<br \/>\nUlrica von Thiele Schwarz, Professor, M\u00e4lardalenUniversity<br \/>\nStefan James, Professor, Uppsala University<\/p>\n<p><strong>15:30 Panel: Strengthening the soundness of academic research<br \/>\n<\/strong>Moderator: Ole Petter Ottersen, President, KI<br \/>\nAstrid S\u00f6derbergh Widding, SUHF Board Chair; President, Stockholm University<br \/>\nJohn P.A. Ioannidis, Professor of Medicine, Stanford University<br \/>\nAnna Dreber Almenberg, Professor of Economics, Stockholm School of Economics<\/p>\n<p>Article written by the main speakers:<br \/>\n<a href=\"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/CIRCRESAHA.114.303819\">Glenn Begley, John P.A. Ioannidis.\u00a0<strong>Reproducibility in Science: Improving the Standard for Basic and Preclinical Research<\/strong>. Circ Res. 2015;116:116-126<\/a><\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41562-016-0021.pdf\">Marcus R. Munaf\u00f2, Brian A. Nosek, John P.A. Ioannidis et al.\u00a0<strong>A manifesto for reproducible science<\/strong>. Nature Human Behavior. 1, 0021, 2017<\/a><\/p>\n<p><a href=\"https:\/\/science.sciencemag.org\/content\/351\/6280\/1433.full\">Colin F. Camerer, Anna Dreber et al.\u00a0<strong>Evaluating replicability of laboratory experiments in economics<\/strong>. Science. 25 Mar 2016: Vol. 351, Issue 6280, pp. 1433-1436<\/a><\/p>\n<p><a href=\"https:\/\/www.nationalekonomi.se\/sites\/default\/files\/NEFfiler\/46-3-adamj.pdf\">Anna Dreber Almenberg och Magnus Johannesson.\u00a0<strong>Vilka forskningsresultat kan vi lita p\u00e5?\u00a0<\/strong>Ekonomisk Debatt. nr 2 2018 \u00e5rg\u00e5ng 46<\/a><\/p>\n<p><a href=\"https:\/\/suhf.se\/aktiviteter\/arskonferens-22-oktober-och-forbundsforsamling-23-oktober-2019-pa-karolinska-institutet\/\">Information p\u00e5 svenska fr\u00e5n SUHF:s hemsida<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We are in the midst of what some have called a research reproducibility crisis. While scientific discovery and complexity are developing at an unprecedented speed, less than 50% of scientific [&hellip;]<\/p>\n","protected":false},"author":100,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3180","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Redefining research quality: Reproducibility and beyond - Ole Petter Ottersen, president Karolinska Institutet 2017-2023<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.ki.se\/rektor\/2019\/10\/21\/redefining-research-quality-reproducibility-and-beyond\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Redefining research quality: Reproducibility and beyond - Ole Petter Ottersen, president Karolinska Institutet 2017-2023\" \/>\n<meta property=\"og:description\" content=\"We are in the midst of what some have called a research reproducibility crisis. While scientific discovery and complexity are developing at an unprecedented speed, less than 50% of scientific [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blog.ki.se\/rektor\/2019\/10\/21\/redefining-research-quality-reproducibility-and-beyond\/\" \/>\n<meta property=\"og:site_name\" content=\"Ole Petter Ottersen, president Karolinska Institutet 2017-2023\" \/>\n<meta property=\"article:published_time\" content=\"2019-10-21T15:26:05+00:00\" \/>\n<meta name=\"author\" content=\"Ole Petter Ottersen\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ole Petter Ottersen\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/2019\\\/10\\\/21\\\/redefining-research-quality-reproducibility-and-beyond\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/2019\\\/10\\\/21\\\/redefining-research-quality-reproducibility-and-beyond\\\/\"},\"author\":{\"name\":\"Ole Petter Ottersen\",\"@id\":\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/#\\\/schema\\\/person\\\/2ab64a284b8dca132a740daeffe56f77\"},\"headline\":\"Redefining research quality: Reproducibility and beyond\",\"datePublished\":\"2019-10-21T15:26:05+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/2019\\\/10\\\/21\\\/redefining-research-quality-reproducibility-and-beyond\\\/\"},\"wordCount\":588,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/#organization\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/2019\\\/10\\\/21\\\/redefining-research-quality-reproducibility-and-beyond\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/2019\\\/10\\\/21\\\/redefining-research-quality-reproducibility-and-beyond\\\/\",\"url\":\"https:\\\/\\\/blog.ki.se\\\/rektor\\\/2019\\\/10\\\/21\\\/redefining-research-quality-reproducibility-and-beyond\\\/\",\"name\":\"Redefining research quality: Reproducibility and beyond - 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