{"id":3919,"date":"2020-06-22T11:01:30","date_gmt":"2020-06-22T09:01:30","guid":{"rendered":"https:\/\/blog.ki.se\/rektor\/?p=3919"},"modified":"2020-06-24T09:19:01","modified_gmt":"2020-06-24T07:19:01","slug":"akademin-och-pandemin-kis-forsta-webbseminarium-om-universitetets-roll-i-en-global-kris","status":"publish","type":"post","link":"https:\/\/blog.ki.se\/rektor\/2020\/06\/22\/akademin-och-pandemin-kis-forsta-webbseminarium-om-universitetets-roll-i-en-global-kris\/","title":{"rendered":"Akademin och pandemin: KI:s f\u00f6rsta webbseminarium om universitetets roll i en global kris"},"content":{"rendered":"

English version below<\/strong><\/em><\/p>\n

P\u00e5 l\u00e4ros\u00e4ten och forskningsinstitutioner v\u00e4rlden \u00f6ver p\u00e5g\u00e5r nu en kraftsamling f\u00f6r att snabbt ta fram relevant kunskap om det nya coronaviruset \u2013 om hur vi ska motarbeta smittspridningen och om hur vi ska kunna utveckla vaccin, l\u00e4kemedel och andra verksamma behandlingar mot covid-19.<\/p>\n

Vi ser hur forskare fr\u00e5n alla delar av v\u00e4rlden arbetar tillsammans f\u00f6r att f\u00f6ra kunskapsutvecklingen fram\u00e5t. Ambitionen och viljan att s\u00e5 snabbt som m\u00f6jligt dela med sig av tidiga forskningsresultat \u2013 \u00f6ppna data p\u00e5 s\u00e5 kallade preprint-servrar \u2013 \u00e4r sl\u00e5ende och gl\u00e4djande. Genom att tillg\u00e4ngligg\u00f6ra data ist\u00e4llet f\u00f6r att \u201dh\u00e5lla p\u00e5 sitt\u201d kan andra forskargrupper, och samh\u00e4llet i stort, komma snabbare fram mot det gemensamma m\u00e5let att besegra pandemin. Covid-19 har \u00e4ndrat mentaliteten bland forskare \u2013 fr\u00e5n att vilja vara f\u00f6rst till att publicera till att vilja vara f\u00f6rst till att dela.<\/p>\n

Det \u00e4r oerh\u00f6rt viktigt att v\u00e5r forskning \u00a0f\u00e5r en central plats i arbetet f\u00f6r att bygga en b\u00e4ttre beredskap inf\u00f6r n\u00e4sta pandemi eller kris. Inte minst: Ett brett forskningsperspektiv m\u00e5ste f\u00e5 ordentligt utrymme i kommissionen som nu ska etableras f\u00f6r \u00a0att f\u00f6lja upp och utv\u00e4rdera den svenska hanteringen av pandemin.<\/p>\n

Beredskap var ett centralt begrepp n\u00e4r KI:s Fakultetsr\u00e5d f\u00f6rra veckan arrangerade ett webbseminarium om akademins betydelse i arbetet mot pandemin: \u201cPandemics: the role of a medical university, now and in the future<\/a>\u201c. L\u00e4s g\u00e4rna\u00a0mitt tidigare blogginl\u00e4gg om evenemanget<\/a>.<\/p>\n

Tidig publicering<\/strong><\/h4>\n

Aldrig i min karri\u00e4r har jag sett nya resultat komma ut s\u00e5 snabbt som nu. Vi befinner oss verkligen p\u00e5 ett snabbt\u00e5g. Tidig publicering av prelimin\u00e4ra forskningsresultat saknar naturligtvis inte risker eller problem. Det \u00e4r inte enkelt att kombinera snabbhet med kvalitet. En s\u00e4rskild utmaning \u00e4r att resultaten normalt blir omedelbart offentliga och tillg\u00e4ngliga ocks\u00e5 utanf\u00f6r forskarv\u00e4rlden. S\u00e4rskilt n\u00e4r det g\u00e4ller ett \u00e4mne med s\u00e5 stort allm\u00e4nintresse som covid-19, \u00e4r det l\u00e4tt att f\u00f6rst\u00e5 att prelimin\u00e4ra, ej granskade, data snabbt kan n\u00e5 journalister som vanligtvis inte arbetar med vetenskapsnyheter \u2013 och som d\u00e4rmed inte f\u00f6rst\u00e5r skillnaden mellan granskade och prelimin\u00e4ra forskningsresultat.\u00a0Paneldeltagarna diskuterade just denna risk och vilket ansvar det inneb\u00e4r f\u00f6r s\u00e5v\u00e4l forskare som f\u00f6r redaktioner. Hur kan forskarv\u00e4rlden tydligare kommunicera att publicerade, men ej sedvanligt granskade resultat \u00e4r os\u00e4kra? Att kommunicera medicinsk forskning \u00e4r utmanande under vanliga betingelser. I det h\u00e4r l\u00e4get \u00e4r det extra sv\u00e5rt och kr\u00e4ver en hel del ansvarstagande fr\u00e5n alla inblandade akt\u00f6rer, s\u00e4rskilt om en forskningspublicering indikerar n\u00e5gon form av uppseendev\u00e4ckande eller kontroversiellt utfall.<\/p>\n

Det blir d\u00e4rmed extra viktigt att forskare finns tillg\u00e4ngliga f\u00f6r medier f\u00f6r att f\u00f6rklara omst\u00e4ndigheterna och den os\u00e4kerhet som kan finnas i resultaten. Det \u00e4r ocks\u00e5 viktigt att vi som universitet g\u00f6r vad vi kan f\u00f6r att s\u00e4kerst\u00e4lla att vi sj\u00e4lva inte bidrar till att \u00f6verdriva betydelsen av prelimin\u00e4ra fynd och att journalister och andra vidaref\u00f6rmedlare av data blir medvetna om detta problem.<\/p>\n

Tillg\u00e5ng till evidens<\/strong><\/h4>\n

En annan aspekt p\u00e5 delvis samma tema och som togs upp p\u00e5 webbseminariet, handlar om vikten av tillg\u00e5ng till evidens och kunskap f\u00f6r politiker och andra beslutsfattare. \u00c4ven h\u00e4r har universiteten och forskarna en mycket viktig uppgift att fylla och det kr\u00e4ver b\u00e5de proaktivitet och tydlighet i kommunikationen.\u00a0 Fr\u00e5gan \u00e4r synnerligen aktuell med tanke p\u00e5\u00a0 den alltmer politiserade diskussionen om den svenska strategin kring pandemin och vem som egentligen har ansvar f\u00f6r vad. Den kommer garanterat ocks\u00e5 upp n\u00e4r det nu snart ska tills\u00e4ttas en kommission som ska utv\u00e4rdera hanteringen. H\u00e4r m\u00e5ste forskning, evidens och kunskap f\u00e5 ordentligt med utrymme ocks\u00e5 med ett fram\u00e5tblickande perspektiv \u2013 vad kan vi ta med oss f\u00f6r l\u00e4rdomar inf\u00f6r n\u00e4sta pandemi eller en framtida samh\u00e4llskris av annan karakt\u00e4r?<\/p>\n

Om det finns ett nyckelord som vi b\u00f6r ta med oss \u200b\u200bfr\u00e5n webbseminariet \u00e4r det just detta: Beredskap. Ett universitet ska arbeta med ett l\u00e5ngsiktigt perspektiv och vi har en s\u00e4rskilt viktig roll att spela f\u00f6r att bygga en global beredskap inf\u00f6r n\u00e4sta pandemi. En pandemi \u00e4r per definition global och vi beh\u00f6ver d\u00e4rf\u00f6r en \u201cuniversal preparedness for health\u201d. Detta \u00e4r i linje med h\u00e5llbarhetsm\u00e5len i FN: s Agenda 2030 och v\u00e5r egen Strategi 2030. Global beredskap kr\u00e4ver l\u00e5ngsiktig forskning av h\u00f6g kvalitet \u2013 och grundforskning, inte minst. Vi m\u00e5ste utveckla vacciner proaktivt, \u00e4ven f\u00f6r virus som \u00e4nnu inte har gett upphov till en epidemi, vi m\u00e5ste utveckla effektiva testsystem som kan finnas p\u00e5 plats fr\u00e5n dag 1, och vi m\u00e5ste fortfarande s\u00f6ka ny och grundl\u00e4ggande f\u00f6rst\u00e5else som \u00e4r f\u00f6ruts\u00e4ttningen f\u00f6r nya behandlingsmetoder. Den kommande forskningspropositionen m\u00e5ste reflektera dessa utmaningar.<\/p>\n

Helhetssyn<\/strong><\/h4>\n

Ut\u00f6ver allt detta m\u00e5ste vi ocks\u00e5 f\u00e5 mer kunskap om hur h\u00e4lsa p\u00e5verkas \u2013 positivt och negativt \u2013 av icke-medicinska interventioner som i m\u00e5nga l\u00e4nder har inneburit att samh\u00e4llet som helhet st\u00e4ngdes. Covid-19 har visat oss att vi som medicinskt universitet m\u00e5ste utveckla en helhetssyn p\u00e5 h\u00e4lsa. Med ett s\u00e5dant helhetssyn kan vi n\u00e4sta g\u00e5ng ge b\u00e4ttre r\u00e5d till expertmyndigheter och politiska beslutsfattare \u2013 om b\u00e5da medicinska och icke-medicinska insatser.<\/p>\n

Viruset, SARS-CoV-2, \u00e4r nytt och \u00e4r fortfarande l\u00e5ngt ifr\u00e5n kartlagt i alla dess detaljer och egenskaper. Kunskapsl\u00e4get f\u00f6r\u00e4ndras och utvecklas st\u00e4ndigt. Vi vet inte \u00e4nnu hur det slutliga utfallet av den h\u00e4r pandemin faktiskt kommer att bli n\u00e4r allt s\u00e5 sm\u00e5ningom ska r\u00e4knas samman. KI:s webbseminarium visar med all \u00f6nskv\u00e4rd tydlighet att vi inom akademin och den medicinska forskningen har en avg\u00f6rande roll att spela f\u00f6r att flytta fram kunskapspositionerna. Vi beh\u00f6ver forska och vi beh\u00f6ver undervisa, men vi beh\u00f6ver ocks\u00e5 vara en aktiv samh\u00e4llsakt\u00f6r. Mycket g\u00f6rs redan \u2013 och g\u00f6rs enast\u00e5ende bra! Annat beh\u00f6ver vi forts\u00e4tta diskutera tillsammans. D\u00e4rf\u00f6r \u00e4r min absoluta f\u00f6rhoppning att vi kan f\u00f6lja upp detta seminarium med flera liknande efter sommaren.<\/p>\n

Stort tack<\/strong><\/h4>\n

Stort tack till Fakultetsr\u00e5det f\u00f6r detta initiativ, inte minst de b\u00e5da moderatorerna Gunilla Karlsson Hedestam och Johan von Schreeb och tack ocks\u00e5 till dem som deltog i panelen: Jan Albert, Soo Aleman, Anna Mia Ekstr\u00f6m, Lars Engstrand, Carina King och Sten Linnarsson. S\u00e4rskilt tack till inledningstalaren Marc Lipsitch och till Elen Hoeg som representerade Coalition for Epidemic Preparedness Innovations (CEPI). Jag vill ocks\u00e5 tacka Carl Johan Sundberg och UoL (KI:s enhet f\u00f6r undervisning och l\u00e4rande) f\u00f6r viktiga bidrag till detta event.<\/p>\n

 <\/p>\n

Academic in the pandemic: KI\u2019s first webinar on the university\u2019s role in a global crisis<\/strong><\/h2>\n

At universities and research institutions around the world, a robust effort is underway to quickly develop relevant knowledge about the new corona virus \u2013 how to reduce the spread of infection, and how to develop vaccines, medications, and other effective treatments against COVID-19.<\/p>\n

We see how researchers around the world are working together to advance our understanding of the disease. The ambition and willingness to quickly share results \u2013 by posting data on so-called pre-print servers \u2013 is remarkable and gratifying to see. Making data easily available is essential if we are to realize our common goal of defeating the pandemic. COVID-19 has changed the mentality among researchers – from aiming to be the first to publish to aiming to be the first to share.<\/p>\n

Our research has an important role to play in building preparedness for the next pandemic or crisis. We were not sufficiently prepared this time around. Moreover, a broad research perspective must be prioritized within the government commission that is now being established to review and evaluate Sweden\u2019s management of the pandemic.<\/p>\n

Preparedness was a central theme in last week\u2019s KI Faculty Council webinar entitled: \u201cPandemics: The role of a medical university, now and in the future<\/a>\u201d.\u00a0 See also my earlier blog on the event<\/a>.<\/p>\n

Early publication<\/strong><\/p>\n

Never before in my career have I seen research data being made available so quickly. Early publication of preliminary results is not risk-free or unproblematic. It is not easy to combine speed with quality. Preliminary data that has not been peer-reviewed can quickly reach journalists that are unfamiliar with the difference between peer-reviewed and preliminary research. At the webinar, panellists discussed this risk and the responsibility it entails for researchers and media. How should scientists communicate uncertainty and controversy, and how should we as academics ensure that we ourselves do not contribute to exaggerating the importance of preliminary findings?<\/p>\n

Access to evidence<\/strong><\/p>\n

Policy makers must have access to relevant evidence and make proper use of it. Notably, the commission that will be established to evaluate how the pandemic has been managed must build its work on the most recent research from academic institutions in Sweden and abroad. Research, evidence, and knowledge must be given proper space in these discussions, not only in assessing past actions, but also in preparing for the next pandemic or societal crisis. This was a central theme in the recent webinar.\u00a0 Strategies to mitigate or suppress infection must be continually informed by research and must be duly sensitive to new data.<\/p>\n

A pandemic is by definition global, and therefore we need a universal preparedness for health<\/em>. This is in line with the UN Agenda 2030 sustainable development goals and our own Strategy 2030. Preparedness requires long-term, high-quality research \u2013 and not least basic research. We must proactively develop vaccines, even for viruses that have not yet caused epidemics, we must develop effective and standardized testing systems that can be in place from day one, and we must continue to seek fundamental knowledge required for new treatments. The upcoming research bill (Forskningsproposition) must reflect these challenges.<\/p>\n

Holistic view<\/strong><\/p>\n

In addition to all this, we must also advance our understanding of how health is affected \u2013 positively and negatively \u2013 by non-medical interventions that in many countries have led to complete lockdowns. How is health impacted by economic recession, unemployment, isolation? COVID-19 has shown us that we must develop a holistic view of health that draws not only on biology and medicine but also on social sciences and the humanities. With such a holistic view we will be able to offer better advice to expert authorities and policy makers \u2013 on medical as well as non-medical interventions. No single university can provide a sufficiently comprehensive view on health. Collaborative efforts are required.<\/p>\n

The virus, SARS-CoV-2, is new and is still far from being mapped in all its details and characteristics. The state of knowledge is constantly changing and evolving. We do not yet know what the final outcome of this pandemic will be. KI’s webinar highlighted the multifarious roles of academia in a global crisis: we need to conduct research and we need to teach, but we also need to communicate facts as well as uncertainty. My genuine hope is that we can follow up on this seminar with several similar ones after the summer.<\/p>\n

Many thanks<\/strong><\/p>\n

My sincere thanks to the KI Faculty Council for taking this initiative, to the two moderators, Gunilla Karlsson Hedestam and Johan von Schreeb, and to those who participated in the panel: Jan Albert, Soo Aleman, Anna Mia Ekstr\u00f6m, Lars Engstrand, Carina King and Sten Linnarsson. A special thanks to keynote speaker Marc Lipsitch and to Elen Hoeg who represented the Coalition for Epidemic Preparedness Innovations (CEPI). Finally, I would like to thank Carl Johan Sundberg and KI’s Unit for Teaching and Learning (UoL) for their important contributions to this event.<\/p>\n

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