{"id":5680,"date":"2021-12-08T19:53:56","date_gmt":"2021-12-08T18:53:56","guid":{"rendered":"https:\/\/blog.ki.se\/rektor\/?p=5680"},"modified":"2022-02-10T09:59:42","modified_gmt":"2022-02-10T08:59:42","slug":"the-nobel-prize-as-a-catalyst-for-progress-on-the-sustainable-development-goals","status":"publish","type":"post","link":"https:\/\/blog.ki.se\/rektor\/2021\/12\/08\/the-nobel-prize-as-a-catalyst-for-progress-on-the-sustainable-development-goals\/","title":{"rendered":"The Nobel Prize as a catalyst for progress on the Sustainable Development Goals"},"content":{"rendered":"\n<p><em><strong>This year\u2019s Nobel Prize in Chemistry is shared by Benjamin List of the Max Planck Institute for Coal Research in Germany and David MacMillan of Princeton University for their independent discovery of small molecules as alternative catalysts (to enzymes and metals) for chemical reactions. This might serve as a welcome example of how basic research can help us move towards the ambitions embedded in the Sustainable Development Goals (SDGs) and UN&#8217;s Agenda 2030.<\/strong><\/em><\/p>\n\n\n\n<p>Many chemical reactions, both biochemical and others, are catalyzed. The concept of catalysis was introduced by J\u00f6ns Jacob Berzelius in 1835. A catalyst is a substance that facilitates a chemical reaction by lowering its activation energy without itself being consumed \u2013 resulting in a more sustainable chemical process of lower overall energy demand.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Future generations<\/h4>\n\n\n\n<p>Catalysis can be for good or for bad, and sustainability is our responsibility to future generations. An important task of universities must be to generate \u201ccounter-innovations\u201d that reduce rather than increase the distance to the SDGs. Together with two of my colleagues I introduced this term \u2013 counter-innovations \u2013 in a recent chapter in the book <em><a href=\"https:\/\/brill.com\/view\/title\/60379\" target=\"_blank\" aria-label=\"undefined (opens in a new tab)\" rel=\"noreferrer noopener\">The Responsive University and the Crisis in South Africa<\/a><\/em>. \u00a0In the present context the discovery of alternative catalysts might help \u201ccounter\u201d the negative effects of the multitude of innovations whose accumulated carbon footprint challenges the planetary boundaries.<\/p>\n\n\n\n<p>Let us look back on another Nobel Prize of relevance to the issue at hand. In 1995 the Nobel Prize in Chemistry was awarded to Paul J. Crutzen, Mario J. Molina and F. Sherwood Rowland, providing a sterling example on how new knowledge and political engagement by scientists can contribute to progress on environmental goals. In this case, knowledge regarding the formation and chlorine-catalyzed decomposition of atmospheric ozone \u2013 processes that are affected by our emissions of various gases \u2013 has enabled sustainable development. <\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Questioned discovery<\/h4>\n\n\n\n<p>Out of Sweden&#8217;s 16 national environmental goals, it is only <a href=\"https:\/\/www.sverigesmiljomal.se\/miljomalen\/skyddande-ozonskikt\/\">the goal of a protective ozone layer<\/a> that is currently achieved. Initially, the discovery that chlorofluorocarbon compounds, or freons, could deplete the ozone layer of the stratosphere was questioned, not least by the chemical industry providing these compounds to refrigeration and freezing systems. A long struggle by the researchers eventually paved the way for the Montreal Protocol in 1987, in which the world\u2019s nations agreed to ban emissions of the harmful gases. What started as research ended up in policy changes that forestalled irreversible damage on human and planetary health.<\/p>\n\n\n\n<p>As mentioned above this year\u2019s Nobel Prize in Chemistry was shared by Benjamin List and David MacMillan for their discovery of small molecules as alternative catalysts for chemical reactions. The use of simple, easily accessible and benign small molecule catalysts such as proline (List\u2019s discovery) and an\u00a0imidazolidinone (MacMillan\u2019s discovery) may contribute to <strong>SDG 12 responsible consumption and production<\/strong> and its targets of a more efficient use of nature\u2019s resources and a reduced amount of toxic waste. That the discoveries have been further developed into highly efficient processes to make chemicals in a much reduced overall number of reaction steps, may contribute to the SDG target on the use of more sustainable methods in industry. \u00a0<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Widely applied<\/h4>\n\n\n\n<p>Asymmetric organocatalysis has been widely applied in the field of medicinal chemistry to prepare for example antiviral, anticancer, neuroprotective, cardiovascular, antibacterial and antiparasitic agents (Han et al. <em>Chem. Soc. Rev.<\/em>, <strong>2021<\/strong>,<em>50<\/em>, 1522\u20131586) related to both communicable and non-communicable diseases of <strong>SDG 3 good health and wellbeing<\/strong>.<\/p>\n\n\n\n<p>Scientific discoveries and innovations have taken us to where we are today \u2013 for good or bad. \u00a0We need to ponder how science can lead us in the right direction \u2013 towards a more sustainable development. Knowing that the health of humans and the health of the planet are inextricably intertwined our mindset must be that every step matters \u2013 be it small or large. \u00a0<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Inspire<\/h4>\n\n\n\n<p>In the Nobel week \u2013 when we are celebrating researchers whose discoveries \u00a0\u201chave conferred the greatest benefit to humankind\u201d &#8211; we are well served to remember the challenges that we as humankind are facing, in the hope that they will inspire scientific endeavors in the years to come. \u00a0<\/p>\n\n\n\n<p><em>Michaela Vallin provided invaluable input to this blog. Her contributions are gratefully acknowledged.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This year\u2019s Nobel Prize in Chemistry is shared by Benjamin List of the Max Planck Institute for Coal Research in Germany and David MacMillan of Princeton University for their independent [&hellip;]<\/p>\n","protected":false},"author":100,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[771,289,26],"tags":[223,743,479,55,341],"class_list":["post-5680","post","type-post","status-publish","format-standard","hentry","category-english","category-nobelpris","category-research","tag-agenda-2030","tag-chemistry","tag-globala-malen","tag-nobel-prize","tag-who"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The Nobel Prize as a catalyst for progress on the Sustainable Development Goals - 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